Thesis (Dip. Paedodont.)--University of Toronto, 1982.
MALIGNANT HYPERTHERMIA (MH) is a pharmacogenetic disease of skeletal muscle that may precipitate a potentially fatal sequence of metabolic responses in the presence of triggering anesthetics. The primary triggers for MH—inhalational anesthetics and succinylcholine—induce an uncontrollable release of intramyoplasmic calcium (Ca 2+) that results in sustained muscle . Patients with neuromuscular disease can suffer from various perioperative problems such as respiratory failure, cardiac failure, malignant hyperthermia-like syndrome, and an . Malignant hyperthermia is an inherited disorder that can be triggered by certain inhaled anesthesia drugs, and causes a fast, extreme rise in temperature and . The North American Malignant Hyperthermia Registry was established in in an effort to centralize, analyze, and disseminate clinical and scientific information about MH to researchers and physicians who care for MH-susceptible by: 4.
Dr. Henry Rosenberg is a Anesthesiologist in Livingston, NJ. Find Dr. Rosenberg's phone number, address, hospital affiliations and more. One example of how drug interactions based on genetic variations can affect clinical practice is the management of malignant hyperthermia (MH). MH is an autosomal dominant condition characterised by hypermetabolism, hypoxia, hypercapnia and hyperthermia resulting from abnormal calcium by: Analysis of histomorphology in malignant hyperthermia-susceptible patients. Reports of Original Investigations. A randomized comparison between records made with an anesthesia information management system and by hand, and evaluation of the Hawthorne effect Book and New Media Reviews. Ovarian cancer is the second most common cause of gynecologic cancer death in women around the world. The outcomes are complicated, because the disease is often diagnosed late and composed of several subtypes with distinct biological and molecular properties (even within the same histological subtype), and there is inconsistency in availability of and access to by:
thermoregulatory responses to cooling in patients susceptible to malignant hyperpyrexia. j. h. ayling, , ph.d diltiazem inhibits halothane-induced contractions in malignant hyperthermia-susceptible muscles in vitro. w. k. ilias, m.d bja: british journal of anaesthesia, vol is october , pages –, https. The evolution of airway management – new concepts and conflicts with traditional practice The evolution of robotic surgery: surgical and anaesthetic aspects Global lessons: developing military trauma care and lessons for civilian practice. A group of X-linked muscle disorders, with their most recognized pathology being Duchenne muscular dystrophy (DMD), followed by Becker muscular dystrophy (BMD) and the relatively new phenotype DMD associated dilated cardiomyopathy (DCM). The most severe phenotype, DMD, usually presents in childhood with a series of developmental motor problems; while BMD, it's a . Effect of Norepinephrine on Intracellular Ca2+ Levels in Malignant Hyperthermia-Susceptible B Cells: Pilot Study in the Search for a New Diagnostic Test for Malignant Hyperthermia The purpose of this study was to determine whether MHS B lymphocytes would demonstrate an increased sensitivity to norepinephrine as indicated by an adrenergic.